An overcrowded, violent maximum-security prison, the end of the line in Alabama's prison system, is dramatically changed by the influence of an ancient intensive meditation program. Behind high security towers and a double row of barbed wire and electrical fence live 1,500 prisoners, many of whom will never again know life in the outside world. But for some of these men, a spark is ignited when it becomes the first maximum-security prison in North America to hold an extended Vipassana retreat, an emotionally and physically demanding program of silent meditation lasting 10 days and requiring 100 hours of meditation. The Dhamma Brothers tells a dramatic tale of human potential and transformation as it closely follows and documents the stories of the prison inmates at Donaldson Correctional Facility as they enter into this arduous and intensive program. The film has the power to dismantle stereotypes about men behind prison bars.