For two decades, a parasitic alien entity known as “The Ick” has benignly crept into every nook and cranny of American life while the residents of small-town Eastbrook remain unconcerned about its existence. Former high school football star-turned-unlucky science teacher Hank (Brandon Routh) and his sarcastic student Grace (Malina Weissman) are thrown together by Grace’s mom’s (Mena Suvari) closely guarded secret and a mutual suspicion that the Ick is about to unleash some monstrous mayhem.